BNIP3 and neoplasm: We observed a significant decrease in the Q score of PTBP2, BNIP3, and Ki-67 in Ptbp2-KO-KCL22 compared to the KCL22-NTC tumor; however, overexpression of BNIP3 in the Ptbp2-KO-KCL22 cells showed a higher Q score (Fig. 6F).