TF1 (human erythroleukemia), HEL (human erythroid leukemia), and F36P (MDS-RAEB) showed varying levels of PTBP2 expression, whereas HNT34 (BCR::ABL1+ human Acute Myeloid Leukemia) cells showed almost no PTBP2 expression among the four AML cell lines (Fig. 1A). Here, PTBP2 is linked to myelodysplastic syndrome with excess blasts.