NR4A2 and bipolar disorder: Layer 2 had enhanced gene expression overlapping the risk of ASD and bipolar disorders, and layer 5 presented enriched gene expression with a risk of schizophrenia.[185] In 2024, spatial transcriptomic arrays were used to evaluate genome‐wide claustrum gene expression in sections from the claustrum of conditional Nurr1 gene‐producing mice in which the Nurr1 gene is known to be a transcription factor that is highly expressed in the claustrum.