Additionally, in animal experiments modeling asthma, administration of full‐length P87‐Sema3E was found to inhibit lung airway remodeling.[22, 23] The discrepancy observed between our findings regarding Sema3E in pulmonary fibrosis and previous studies in asthma prompted us to delve deeper into understanding the underlying mechanisms. The gene discussed is SEMA3E; the disease is asthma.