PCSK9 and atherosclerosis: Whole aortas of Hm13mKO rAAV8‐Pcsk9 mice exhibited less atherosclerosis, and those of Hm13mOE rAAV8‐Pcsk9 mice exhibited enhanced atherosclerosis, relative to Hm13fl/fl rAAV8‐Pcsk9 controls (Figure 4h).