CDK2AP1 and lip and oral cavity carcinoma: In a previous study from our laboratories, the expression and functional analysis of the CDK2AP1 gene (also known as DOC1, Deleted in Oral Cancer), encoding for a key NuRD subunit, has revealed its central role in the “tug-of-war” between the NuRD and SWI/SNF chromatin remodeling complexes for the activation/repression of master regulators of epithelial-to-mesenchymal transition (EMT).18