Computational analysis of the digital scans of the stained TMAs, implemented with the recently published SPIAT tool,49 allowed us to further improve Visiopharm analysis, not only by resolving the tumor parenchyma from the stroma but also by establishing the composition of immune cells in the TME, their spatial distribution, and relative abundance in relation to CDK2AP1 status. The gene discussed is CDK2AP1; the disease is neoplasm.