Uncontrolled activity of STING results in manifestation of autoinflammatory diseases, e.g., STING-associated vasculopathy with onset in infancy (SAVI) (Liu et al., 2014), Parkinson’s disease (Hinkle et al., 2022), or severe COVID-19 disease (Domizio et al., 2022). This evidence concerns the gene STING1 and Parkinson disease.