CACNA1A gene variants have been associated with various seizure disorders, including recurrent febrile seizures, early-onset febrile and afebrile status epilepticus, generalized seizures (such as absence seizures, myoclonic-astatic seizures, and tonic–clonic seizures), focal seizures, and rarely epileptic spasms. The gene discussed is CACNA1A; the disease is status epilepticus.