GFAP and Alzheimer disease: Studies in induced pluripotent DS stem cells suggest abnormal neuronal differentiation affecting neuronal architecture and density as well as a number and length of neurites, and differentiation into GFAP‐positive cells, thereby promoting a shift from the neuronal to the astroglial and oligodendroglial phenotype,50, 51 which could facilitate later developments of neuroinflammation and AD pathology.