The individual proteins in the myopathy‐elevated set (n = 30) were strongly associated with skeletal muscle through tissue enrichment and/or pathway involvement and include a mix of cytosolic metabolic proteins (CKM, GPD1, FBP2, ENO3, etc.)and proteins associated with contractile elements (MYOM2, MYOM3, TNNI2, ACTN2, and PDLIM3), indicating the presence of both structural damage as well as membrane leakage in these individuals. This evidence concerns the gene ENO3 and myopathy.