The expression of NF‐ĸB in colonic tissues of dogs fed WD was significantly increased (p < 0.001) compared to colonic expression in dogs fed CD (NF‐ĸB area: CD1, 8.09% ± 3.3%; WD, 11.58% ± 3.4%; CD2 7.25% ± 3.8%; 95% CI; Figure 3A,B). Here, CD2 is linked to Wilson disease.