KIR2DL1 and viral infectious disease: Gene KIR2DL1 (killer cell immunoglobulin-like receptor, two Ig domains and long cytoplasmic tail 1) located on chr19: 55276166-55295820 (hg19) was reported to be associated with Behcet syndrome and viral infection.48, 49, 50 This indicated that copy number loss of gene ZNF717 and KIR2DL1 may lead to viral infection-induced pathological conversion of corneal endothelial cells in ICE syndrome.