Furthermore, the expression of potassium channel multimer domain protein 20 antibody (KCTD20) and lncRNA-NEAT1 are highly linked in the clinical sample experiment, the decreased expression of lncRNA-NEAT1 and KCTD20 can also lead to the inhibition of the expression levels of cyclin proteins (Cyclin-Dependent Kinases4 and Cyclin D1) and apoptosis-related protein Bcl-2, while the level of pro-apoptotic protein Bax is upregulated, which causes the glioma cell proliferation efficiency to decline and increases the percentage of apoptosis to a certain extent. The gene discussed is NEAT1; the disease is central nervous system cancer.