It is significantly upregulated in sepsis patients and contributes to disease progression by regulating inflammatory factors (Wei et al., 2020) Lipopolysaccharide (LPS)-induced inflammation and apoptosis are mediated through the NEAT1/miR-370-3p axis (Wu et al., 2020), playing a central role in the initiation of sepsis. The gene discussed is NEAT1; the disease is Sepsis.