At the same time, in patients with MS, the transcriptional activation of interleukin 8 (IL-8) (Santoro et al., 2016) may be related to the induction of lncRNA-NEAT1 through the stathmin-activated Toll-like receptor III-mitogen-activated protein kinase 13 (TLR3-p38) pathway. The gene discussed is NEAT1; the disease is myeloid sarcoma.