In the study (Pan J. et al., 2022) of Pan et al., it has been found that overexpression of lncRNA-NEAT1 promotes the migration and invasion ability of HCC cells, and also promotes the transcriptional activity of PKM2, and the knockdown of lncRNA-NEAT1 can inhibit the transcriptional activity of PKM2. Here, PKM is linked to hepatocellular carcinoma.