The study showed that lncRNA-NEAT1 can directly bind miR-124-3p, promoting high expression of adipose triglyceride lipase, free fatty acid and diacylglycerol, and activating PPARα to promote the occurrence and development of HCC (Liu et al., 2018), therefore, lncRNA-NEAT1 may become a new therapeutic target for HCC. This evidence concerns the gene PPARA and hepatocellular carcinoma.