ZFAS1 plays a significant role in several other malignancies such as hepatocellular carcinoma [5], oral squamous cell carcinoma [6] cervical carcinoma [7], thyroid cancer [8], cholangiocarcinoma [9], glioma [10], endometrial carcinoma [11], pancreatic cancer [12], osteosarcoma [13], colorectal cancer [14], gastric cancer [15], and nasopharyngeal carcinoma [16] as shown in Fig. 1. Here, ZFAS1 is linked to osteosarcoma.