Yao et al. [127] demonstrated that tumor-derived circRNA_102191 is a competing endogenous RNA of XPR1 that absorbs miR-493-3p, ultimately promoting the proliferation, migration, and invasion of GC cells by promoting the polarization of M2-type macrophages, as well as enhanced EMT by boosting the level of Vimentin and suppressing the level of E-cadherin. Here, CDH1 is linked to gastric cancer.