IL1B and hepatocellular carcinoma: In hepatocellular carcinoma, the level of CXCL11 secreted by CAFs was considerably elevated compared with that of normal fibroblasts, and CXCL11 stimulated the upregulation of circUBAP2 expression, which further indirectly affected the levels of IL-17 and IL-1β by inhibiting miR-4756 expression [134].