MiR-127-5p overexpression in hepatocellular carcinoma cells enhances EMT progression by accelerating the activation of the SHC3/ERK signaling pathway to upregulate the expression of Vimentin and N-cadherin, suggesting that circRNAs could promote EMT by accelerating T-cell apoptosis [107]. This evidence concerns the gene CDH2 and hepatocellular carcinoma.