Chen et al. [85] illustrated that the substantially upregulated hsa_circRNA_102051 is involved in the tumorigenesis of CRC by activating as a miR-203a sponge, which alleviates the inhibitory effect of miR-203a on Notch1 and BPTF and enhances the stemness of the cancer cells, indicating that hsa_circRNA_102051 may regulate EMT through the miR-203a/Notch1 axis. The gene discussed is NOTCH1; the disease is cancer.