Due to the development of thrombocytopenia and recurrent multi-territory strokes, an ADAMTS13 (a disintegrin and metalloprotease with a thrombospondin type 1 motif, member 13) screen was ordered and was positive. The ADAMTS13 activity was <5%, while the ADAMTS13 inhibitor Bethesda titer was notably high (1.4, normal <0.4). This evidence concerns the gene ADAMTS13 and Thrombocytopenia.