In lipopolysaccharide (LPS) -induced ALI, activation of SIRT1 by Meteorin-like/Meteorin-β and fibroblast growth factor (FGF) reduces ferroptosis and protects lung tissue by inhibiting p53 acetylation and Nrf2 (Chen et al., 2023b; Lin et al., 2024b). The gene discussed is SIRT1; the disease is acute respiratory distress syndrome.