NFKB1 and rheumatoid arthritis: Analysis, by western blot, of cell lysates from DCs showed that RA patient EMVs, as well LPS, induced a significant increase of p38 (Figure 3A), ERK (Figure 3B) and NF-κB p65 (Figure 3C) phosphorylation, compared to both untreated and HD EMVs treated cells.