DPP6 and multiple sclerosis: A study on multiple sclerosis in the Nordic population showed that DPP6 levels were elevated in PBMCs of PrMS patients, although DPP6 is known to be mainly expressed in the brain and spinal cord, and DPP6 downregulation was observed in spinal motor neurons induced by SBMA iPSC differentiation (Brambilla, 2012; Sheila, 2019).