Hemodiafiltration (HDF) with (V‐RATM) and without a vitamin E‐coated hemodiafilter (ABHTM) was performed in an acute kidney injury pig model to determine whether changes in the serum albumin, the oxidized albumin (OxiALB), and the reduced albumin (RedALB) levels differ between the two groups. Here, ALB is linked to acute kidney injury.