CD8A and neoplasm: Phenotypic profiles of CD8+ T cells in TDLNs showed that YD‐treated CD8+ T cells predominantly differentiated into central memory (Tcm) cells (Figure 6C), known for their role in systemic immune surveillance and as a reservoir for long‐term immunity.[46, 47] Assessment of tumor specimens revealed that most of the infiltrated CD8+ T cells from YD treatment were Tem/effector, known for their high cytotoxicity upon tumor antigen reactivation,[48] with very few Tcm cells left in the tumor.