OSBPL9 and neuroblastoma: Additionally, the growth environment of in vitro cultured neuroblastoma cell lines differs from that in patients, and combined with the high heterogeneity of neuroblastoma itself [35], further validation with more clinical data and samples is still required OSBPL9 belongs to the oxysterol-binding protein-like (OSBPL) family, which comprises essential transport proteins on cell membranes that facilitate molecular or signal exchange between organelles, primarily involved in cellular lipid and cholesterol metabolism [36].