Similarly, other series concluded increased serum level of soluble MIC-B in many cancers in relation to the normal controls including gastrointestinal carcinomas, oral squamous cell carcinoma, and lung cancers (Garrido-Tapia et al. 2017; Tamaki et al. 2010; Cascone et al. 2017). The gene discussed is MICB; the disease is digestive system carcinoma.