We also performed RNA-seq analysis on these purified tumor-infiltrating CD3+ cells and found that those from the T28zT2 group exhibited upregulation of genes related to pathways involved in T cell receptor (TCR) signaling, NK cell-mediated cytotoxicity, IFN-γ-mediated signaling, and the regulation of T cell proliferation (Figures S3D–S3G; Tables S3 and S4). The gene discussed is IFNG; the disease is neoplasm.