Indeed, the RAGE−/− GLO+/+ genotype was associated with significantly lower MG plasma concentrations in experimental sepsis (Fig. 3d) as well as a significantly increased survival rate in comparison with wild-type mice (survival: wild-type C57/BL6 mice 6/15 [42.9%] vs. RAGE−/− GLO+/+ mice 7/9 [77.8%]; HR = 0.2 [95% CI 0.07–0.65], p ≤ 0.03, Gehan–Breslow–Wilcoxon method; Fig. 3e). The gene discussed is MGAM; the disease is Sepsis.