In a study performed by Caponnetto et al., GSC-derived EVs isolated from glioma tissues after patient surgery showed high levels for CD105, SSEA-4, CD44, CD29, and CD20 and low levels for CD56, CD25, CD49e, ROR1, HLA-ABC, MCSP, and CD133 [40]. The gene discussed is PROM1; the disease is central nervous system cancer.