Recently, a study performed by Franceschi et al. showed that CD105, CD133/1, CD14, CD142, CD146, CD29, CD44, CD56, HLA-DR/DP/DQ, MCSP, and the three tetraspanins CD9, CD63, and CD81 had high levels on the surface of the GBM explant-derived EVs [39]. This evidence concerns the gene CD81 and glioblastoma.