After having discovered tens of BCL2L12 circRNAs in the 7 CRC cell lines and predicted their interactions with particular miRNAs, we sought to answer the question whether a remarkable change in the levels of BCL2L12 circRNAs comprising part of the 3′-untranslated region (3′-UTR) of BCL2L12 mRNA could significantly affect the levels of this latter. This evidence concerns the gene BCL2L12 and colorectal carcinoma.