Tong et al.20 observed that, while Zucker lean rats exhibited minimal increases in triglycerides and cholesterol on high-fat diets, Zucker fat rats displayed elevated levels of these lipids, reflecting a higher risk of hepatic steatosis and dyslipidemia, as well as increased susceptibility to liver damage, as evidenced by alanine transaminase concentration. This evidence concerns the gene GPT and Hepatic steatosis.