LRP4 and myasthenia gravis: Myasthenia gravis (MG) is a chronic autoimmune disorder characterized primarily by muscle weakness and fatigue, attributed to the disruption of neuromuscular transmission due to autoantibodies targeting the acetylcholine receptor, muscle-specific kinase (MuSK), and lipoprotein receptor-related protein 4 (LRP-4) at the neuromuscular junction and causing structural and functional changes in the postsynaptic membrane [1–11].