Subsequently, we employed the LASSO regression model (Figure 2) to further refine our variable selection, and based on this analysis, we selected nine variables of significant importance for predicting the prognosis of stroke patients: National Institutes of Health Stroke Scale (NIHSS), Barthel Index (BI), Watanabe Drinking Test (KWST), Apolipoprotein A1 (ApoAI), Platelet Distribution Width (PDW), Aortic Stenosis (AS), Smoking History, Diabetes, and Hypertension. This evidence concerns the gene APOA1 and aortic stenosis.