EVs-impacted neutrophils exhibited increased lifespan, chemotactic ability, and released higher levels of neutrophil extracellular traps (NETs), reactive oxygen species (ROS), IL-8, vascular endothelial growth factor (VEGF), and MMP9, alongside upregulated CD184 expression, ultimately promoting tumor cell migration and viability. The gene discussed is VEGFA; the disease is neoplasm.