SEMA3E and cancer: Figure 2C illustrates significant dysregulation of SEMAs in these cancer types relative to their corresponding ANTs. SEMA3E was notably downregulated in 13 cancer types, except for uterine corpus endometrial carcinoma (UCEC), where no significant downregulation was observed. The detailed expression of SEMA3E in the 14 cancer types and their corresponding ANTs is exhibited in Figure 2D.