Significantly, latent TGF‐β‐binding protein 1 (LTBP1) can affect the changes in inflammation‐related pathways by activating the TGF‐β/Smad signaling pathway and stimulate the development of epilepsy, and the regulation of epilepsy occurrence with neuroprotection can be achieved through the inhibition of LTBP1 expression.73 This evidence concerns the gene TGFB1 and epilepsy.