For patients with cancer, we searched for individual factors associated with the development of anti-αGal IgE by analyzing the distribution of the population with respect to age, sex, metastatic status, alcohol and tobacco consumption, clinical allergy, and atopic biological markers (Supplementary Table S2, available at https://doi.org/10.1016/j.iotech.2025.101041). Here, IGHE is linked to allergic disease.