METTL3 and neoplasm: To investigate the role of METTL3 in HCC, we initially analyzed the expression profile of METTL3 in HCC and control liver tissues from data in the Cancer Genome Atlas (TCGA) database and The Human Protein Atlas (HPA) database (tandem mass tag (TMT) mass spectrometry data of paired tumor and adjacent nontumor liver tissues originally from the CPTAC dataset [24]).