We have found that PRKCQ‐AS1 is overexpressed in MYCN nonamplified human neuroblastoma cell lines due to transcriptional super‐enhancers, and that PRKCQ‐AS1 RNA interacts with MSI2 protein to induce BMX mRNA stabilization and overexpression, resulting in neuroblastoma cell proliferation and tumor progression. The gene discussed is PRKCQ-AS1; the disease is neoplasm.