Super‐enhancers are associated with critical oncogenes and substantially up‐regulate the expression of the associated oncogenes.[2, 3, 4] To examine the cause for PRKCQ‐AS1 overexpression in MYCN‐nonamplified neuroblastoma cells, we analyzed published chromatin immunoprecipitation sequencing (ChIP‐Seq) data with antibodies against acetylated histone H3 lysine 27 (acetyl H3K27), the marker for transcriptional super‐enhancers. Here, MYCN is linked to neuroblastoma.