Despite the upregulation of SLC7A5 in effector T cells under inflammatory conditions stimulated by the inflammatory factor IFN‐γ, the large amount of Kyn produced by tumors competes for SLC7A5 binding (partially explaining the reduced Trp acquisition in effector T cells within the tumor microenvironment), affecting effector T‐cell growth and proliferation [118]. This evidence concerns the gene IFNG and neoplasm.