Huang et al. used microarray technology, GO enrichment, and KEGG pathway analysis to show that monocyte infiltration-related genes were highly expressed in pemphigus patients' skin lesions, with dense neutrophil infiltration, high expression of the IL-17 signaling pathway in skin lesions and peripheral blood monocytes, and peripheral blood monocytes responded abundantly to IL-1.18 The gene discussed is IL1B; the disease is pemphigus.