It has been found that the severity of COVID-19 is related to the levels of pro-inflammatory cytokines and cellular immune features.[7] It was found that after SARS-CoV-2 infection, patients had increased level of various cytokines in their plasma, including IL-1β, IL-1 RA, IL 4, IL-7, IL-8, interleukin-10 (IL-10), MIP-1α, MCP-1, IFN-γ, G-CSF, and TNF-α. The gene discussed is IL1B; the disease is COVID-19.