PTEN and multinodular goiter: This patient had PTEN testing years later at age 35 due to personal medical history (keratotic pits of the palm, oral papillomas, multinodular goiter and macrocephaly) and presented with a pathogenic germline PTEN single nucleotide substitution in intron 2 affecting the splice site (NM_000314.8: c.165-1G > A, p.()?