Nevertheless, we found no significant differences between groups in the proliferation rate of tumor-infiltrating Treg cells (Supplemental Figure 4J), their FOXP3 and CD25 protein levels measured by flow cytometry (Supplemental Figure 4, K and L), and the relative proportion of central versus effector Treg cell subsets (Supplemental Figure 4M). The gene discussed is IL2RA; the disease is neoplasm.