GDF15 and cancer: Lastly, diclofenac's ability to induce apoptosis is further supported by its role in increasing the expression of the nonsteroidal anti‐inflammatory drug‐activated gene 1 (NAG‐1).[15] NAG‐1 is associated with proapoptotic activities in various cancer types, underlining diclofenac's multifaceted approach to inducing cancer cell apoptosis through both direct and indirect mechanisms.