Indeed, similar to results observed with the immunoblot kinase array, F62 NHLF relative phosphorylation levels across treatment with all n = 5 OS cells demonstrated significant increases in HSP27, p38, and ERK1/2 phosphorylation relative to NHLF treatment with exosomes derived from non-OS tumor cell lines (Fig. 3C); however, no statistically significant phosphoproteins were upregulated in the AKT/mTOR pathway (Supplementary Fig. S1). The gene discussed is MAPK3; the disease is neoplasm.