To begin to address this gap in knowledge about TBXT expression regulation, we have used circularized chromosome conformation capture coupled with next‐generation sequencing (4C‐seq) [19, 20] to capture, at high resolution, genomic regions that interact with the TBXT promoter, which may represent potential cis‐regulatory elements (pCREs) in lung cancer cell lines. This evidence concerns the gene TBXT and lung cancer.