CD63 and CD81 expression are associated with tumor invasion and tumor growth, respectively.50,51 Additionally, a total of 119 miRNAs were altered, of which 23 were associated with thyroid cancer.41 These included the downregulation of hsa-miR-429, hsa-miR-199, and hsa-miR-128-3p, which have been described as tumor suppressors.52-54. The gene discussed is CD81; the disease is neoplasm.