To further investigate its role, we examined the correlation of C3 expression with three classical markers associated with PCOS: follicle-stimulating hormone receptor (FSHR), cytochrome P450 family 19 subfamily A member 1 (CYP19A1), and C-reactive protein (CRP) (Figures 4A, B). Here, CYP19A1 is linked to polycystic ovary syndrome.