SLC6A19, functioning as a sodium-coupled neutral amino acid transporter, plays a pivotal role in the intestinal absorption of amino acids derived from dietary proteins and in the renal reabsorption of filtered amino acids (45).In one article, a decrease in SLC6A19 expression within ccRCC tumor tissues was noted, corroborating the findings of our research. Here, SLC6A19 is linked to nonpapillary renal cell carcinoma.