MTOR and cardiovascular disorder: In the mammalian and human heart, both mTORC1 and mTORC2 complexes of the mTOR signaling pathway play critical roles in cardiac physiology and the pathology of cardiovascular diseases, including cardiac fibrosis and inflammation (Lu et al., 2023; Sciarretta et al., 2022; Sciarretta et al., 2018; Gao G. et al., 2020).