Statistical analysis showed a significant decrease in the expression of the CD14 marker in all probiotic groups (Del, Ram, and Mix) compared to the LPS group in both healthy and RA patient‐derived macrophages (in controls, pDel vs. LPS < 0.0001, pRam vs. LPS < 0.0001, pMix vs. LPS < 0.0001 and in RA patients, pDel vs. LPS < 0.0034, pRam vs. LPS = 0.0005, pMix vs. LPS = 0.0027) (Figure 7A). The gene discussed is CD14; the disease is rheumatoid arthritis.