THBS1 and lung adenocarcinoma: Bai et al. (2010), Papadaki et al. (2009) reported that in patients with gastric cancer, the 5-year OS rate of patients with high Txr1 expression was lower compared with patients demonstrating the converse. Papadaki et al. (2009) reported that, in patients with lung adenocarcinoma, the survival rates of patients demonstrating low Txr1 and high TSP1 expression levels were higher than those with high Txr1 and low TSP1 expression. Similar results were demonstrated in non-small cell lung cancer patients (Papadaki et al., 2011).