KDM1A and small cell lung carcinoma: Using human SCLC cell lines and immunocompetent animal models, researchers assessed Lysine-Specific Demethylase 1 (LSD1)’s impact on MHC-I expression, functional antigen presentation, and immune activation in SCLC in vitro and in vivo. By explicitly blocking LSD1, researchers were able to promote the transcription of genes related to the antigen presentation pathway and reestablish MHC-I cell surface expression in SCLC.